Bone growth

Healing in the Form of Bone Growth

May 28th, 2014

140318093220-largeOral cancer has been seen to take a cruel toll on many individuals. It has silenced the voice of a famous film critic and even brought an NBA coach to tears.

Surgery has been a means to treat cancer that has spread to the salivary gland; however, complications have lead to significant loss of bone, and even in some patient, the entire lower jaw. While oral cancer is truly an ordeal to go through, the aftermath, beyond the treatment, can be just as devastating. Disfigurement is something that patients often have to face; it’s certainly not something that people easily can swallow.

However scientists have been looking into more ways to fight back and keep disfigurement from being what is inevitable for patients. Dentists have discovered a new method allowing for bone to repair. Bone repair isn’t an impossible task, but there are certain criteria that need to be fulfilled After a fracture, the fragments of bone are only able to come together and fuse of they are in close proximity to each other. The growth of bone involves connective tissue that later calcifies, which provides the platform that allows for the formation of functional bone.

When there is too big a gap between two bone fragments or when bones have been too damaged, the body has a harder time repairing. Researchers have found created synthetic bone material that has been successful at stimulating material in the bone. This artificial scaffolding is found to be as strong as real bone but is porous enough to allow bone tissue and blood vessels to grow. For the process to move along faster, the scientists incorporated stem cells that have received directions in creating bone.

Research has shown that this new method has been successful on various animals, and during this year, the researcher hope to take this to clinical studies on patients with serious gum disease or mandibular bone damage. This field of research fosters hope and provides patients with the opportunity to push back and move past cancer.

If you have any more questions, feel free to contact Drs. Ali & Ali and the caring team at Wellesley Dental Group if you have any thoughts or concerns; they will be happy to answer your questionsContact us today at 781-237-9071 or smile@wellesleydentalgroup.com to set up an appointment and consultation.

 

References:
http://www.cnn.com/2010/HEALTH/02/19/george.karl.throat.cancer/
http://www.sciencedaily.com/releases/2014/03/140318093220.htm
http://www.esquire.com/features/roger-ebert-0310

Is the Future of Dental Implants Found In Diamonds or Titanium?

October 25th, 2013

 

 

diamond

 

It may be strange to think that a precious jewel can aid in the field of dentistry. Researchers at UCLA have been looking into diamonds and if they do have a place in creating better dental implants for patients. These researchers are focusing on nanodiamonds, which are made through conventional mining and refining operations and are definitely called “nano” for a reason; they come out to be approximately four to five nanometers in diameters, resembling miniature soccer balls. The UCLA researchers enlisted the help of the UCLA School of Dentistry, the UCLA Department of Bioengineering, Northwestern University, and even the NanoCarbon Research Institute in Japan to help come up with innovative ways to implement these nanodiamonds in dentistry. Their research has led them to believe that these nanodiamonds can improve bone growth and has the potential to counteract osteonecrosis, a disease marked by bone breakdown due to reduce blood flow.

 

Osteonecrosis can affect various parts of the body, but when this disease affects the joints in the jaw, it can keep people from eating and speaking properly, even restricting or impeding movement. What makes matters worse is that when osteonecrosis occurs near implants, including teeth or prosthetic joints, these implants loosen and can eventually fall out. These dental implant failures lead to additional procedures, which can not only be painful, but can also become very expensive.

 

These issues surrounding dental implants led the team at UCLA to conduct a study that would reveal whether nanodiamonds would be a viable solution. Conducted by Dr. Dean Ho, a professor of oral biology and medicine at the UCLA School of Dentistry, and his team used the nonadiamonds to deliver proteins responsible for bone growth. Their results indicated that nanodiamonds have the uncanny ability to bind rapidly the essential proteins and growth factors. The surface properties of these diamonds allow for a slower delivery of these proteins, which researchers believe contribute to a longer period of treatment of the affected area in the oral cavity. What’s more is that these nanodiamonds can be inserted in to patients in a non-invasive way, through either an injection or an oral rinsing.

 

Nanodiamonds are not only the technology that researchers are pursuing to improve. On the other side of the world, researchers in Japan and China have been revisiting the essential components of titanium, which contains alloys that are very commonly used in orthopedic implants. Because of its reliable mechanical and chemical properties, along with its biocompatible and corrosion resistant nature, titanium has been the go-to product to use in dental implant procedures. However, one of the drawbacks that titanium faces is its lack of ability to bond directly to living bone. Researchers have found that calcium phosphate (CaP) and collagen are main components of natural bone; these scientists believe that a composite of both of these components can be used to effectively coat titanium implants. The study they published in the journal of Science and Technology of Advanced Material showed that when titanium implants were coated with CaP gel and inserted into the thigh bone of rabbit, within four and eight weeks, the authors noticed that there was significantly more new bone on the surface of the titanium implants that had been covered with the CaP gel. These coated implants were also able to bond directly to the bone, without needing an intervening soft tissue layer. The researchers believe that this innovative CaP and collagen composite can play an important role in improving dental implants.

 

Both results found for nanodiamonds and titanium prove to be exciting news in field of Periodonistry and even in the medical world as a whole. These nanodiamonds may possibly revolutionize dental implants, allowing them to be longer lasting and effective, while this the new CaP and collagen coating and greatly improve the use of titanium. Feel free to contact Drs. Ali & Ali and the caring team at Wellesley Dental Group if you have any thoughts or concerns; they will be happy to answer your questions! Contact us today at 781-237-9071 or smile@wellesleydentalgroup.com

 

References:

 

http://www.sciencedaily.com/releases/2013/09/130918102002.htm

http://www.sciencedaily.com/releases/2013/10/131003142214.htm

http://newsroom.ucla.edu/portal/ucla/nanodiamond-encrusted-teeth-248066.aspx

http://news.sciencemag.org/health/2011/03/nanodiamonds-could-be-cancer-patients-best-friend

http://www.abcnetspace.com/2013/08/how-diamonds-are-shaping-technology.html to read more about Diamond Technology!

 

 

 

 

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