RA

Connection Between Periodontitis and Rheumatoid Arthritis

June 27th, 2015

 

It's no doubt that oral health is a window to overall health. There is a significant amount of research linking common oral problems to heart disease, diabetes, pneumoniaAlzheimer’s disease, and now rheumatoid arthritis (RA). Rheumatoid arthritis is a chronic inflammatory disease affecting the joints, which typically causes pain and stiffness. There is increasing interest in the relationship between oral health and inflammatory diseases. A recent study conducted in March of 2015 suggests that periodontitis, a type of inflammatory disease affecting the supportive structures of the teeth (such as bones and tissues), along with rheumatoid arthritis are associated with Porphyromonas gingivalis (P. gingivalis) and may trigger the development of rheumatoid arthritis.The study titled "Inflammation in the Mouth and Joints in Rheumatoid Arthritis," was presented at the 93rd General Session and Exhibition of the International Association for Dental Research. The study examined 8 chronic RA patients, 15 onset RA patients, and 20 individuals with neither periodontitis nor RA. Of the total 23 RA patients, 10 had gingivitis and 9 had periodontitis. In addition, 6 of the individuals with both periodontitis and RA also had P. gingivalis, a strain of bacterium in the oral cavity that is typically associated with the cause of periodontal disease.

Researchers also found that regardless of dental care, all RA patients showed oral inflammation. They suggest that P. gingivalis antibodies may help rheumatologists in distinguishing RA patients who may benefit from periodontal treatment.

Both RA and periodontal disease are similar in many ways. Smoking is a common risk factor of RA and periodontal disease and should be avoided. individuals with RA have a higher risk of developing periodontal disease and may experience more severe symptoms.

It is clear that inflammation and oral bacteria may go hand-in-hand. Take good care of your teeth, it can ultimately save your joints!

Feel free to contact Drs. Ali & Ali and the caring team at Wellesley Dental Group if you have any thoughts or concerns; they will be happy to answer your questions! Contact us today at 781-237-9071 or smile@wellesleydentalgroup.com to set up an appointment and consultation.

Your little ones and teens are welcome to visit our pediatric dentist Dr. VanDr. Emad is happy to help with your orthodontic needs. For wisdom teeth extractions or any other oral surgery needs Dr. Ghazi would be more than willing to help.

References:

http://www.sciencedaily.com/releases/2015/03/150312123526.htm

http://www.cadentalgroup.com/wp-content/themes/custom-theme/img/slider/dentist-1.jpg

Finding the Bacterial Link Between Rheumatoid Arthritis and Gum Disease

September 16th, 2013

Over the years, researchers have been able to demonstrate the importance of oral health in relation to systemic, or overall, health. Keeping up with oral hygiene has been shown to not only affect the oral cavity, but also various areas in the body. Oral health has been linked to the prevalence of rheumatoid arthritis (RA), diabetes, cardiovascular disease, osteoporosis, Alzheimer’s disease, and various other conditions. Researchers have been well aware of the strong association between oral health and these health conditions, but continue to look into the root cause and mechanisms that result in these links.

 

However, a research group at the University of Louisville School of Dentistry Oral Health and Systemic Diseases recently published their findings in PloS Pathogens, revealing the bacterium that is responsible for periodontal disease.  They found that the bacterium, Prophromonas gingivalis, leads to a faster progression of gum disease, increasing cartilage and bone destruction. Their research indicated that P. gingivalis produces an enzyme, peptidylarginine deiminanse (PAD), which increases collagen-induced arthritis (CIA). This enzyme makes the body believe that there are intruding proteins within the body, inducing an immune attack. This results in chronic inflammation, which accounts for the weakening of bone and cartilage within the joints.

 

This research group was able to show that there is a viable link between P. gingivalis periodontal infection and rheumatoid arthritis; however, more research needs to be done to verify these finds. Hopefully further research can bring about new strategies to prevent RA. These studies also should encourage individuals to maintain good oral hygiene. It is always important to keep in mind that brushing and flossing not only keeps the mouth clean, but also keeps the entire body healthy. Please feel free to contact Drs. Ali & Ali and the caring team at Wellesley Dental Group if you have any thoughts or concerns; they will be happy to answer your questions! Contact us today at 781-237-9071 or smile@wellesleydentalgroup.com

 

 

References:

http://www.mayoclinic.com/health/dental/DE00001

http://www.sciencedaily.com/releases/2013/09/130912203327.htm

http://www.genengnews.com/gen-news-highlights/how-bad-gums-lead-to-arthritis/81248849/

http://arthritisbroadcastnetwork.org/2013/09/gum-disease-may-be-an-indication-of-rheumatoid-arthritis/

 

 

 

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